Melrose Homes for Sale

Welcome to Melrose, a tranquil and charming subdivision nestled in the heart of Charleston, South Carolina. Known for its picturesque surroundings and vibrant community spirit, Melrose offers an ideal blend of Southern charm and modern living. This delightful neighborhood is perfect for families, retirees, and anyone seeking a peaceful retreat while still enjoying the conveniences of city life.

Melrose boasts a variety of homes for sale, catering to diverse tastes and lifestyles. From cozy single-family residences to spacious modern homes, the architecture reflects a harmonious balance of traditional Southern design and contemporary flair. Each property is thoughtfully designed, featuring open floor plans, lush gardens, and inviting outdoor spaces that encourage relaxation and community gatherings.

Residents of Melrose enjoy easy access to Charleston’s rich history and culture. Just a short drive away, you can explore the historic downtown area, with its cobblestone streets, vibrant dining scene, and unique boutiques. The nearby parks and recreational facilities provide ample opportunities for outdoor activities, whether it’s a leisurely stroll, a picnic with family, or a weekend of fun at the local playground.

With homes for sale in Melrose, you have the chance to become part of this welcoming community. Experience the warmth of Southern hospitality, the beauty of Charleston’s landscape, and the comfort of a neighborhood that feels like home. Don’t miss out on the opportunity to find your dream home in Melrose, where every day feels like a vacation in this enchanting part of South Carolina.

Newest Melrose Homes for Sale

$1,599,000

4 Beds ⋅ 6 Baths ⋅ HILTONHEAD-512881 MLS

Direct oceanfront living on Daufuskie Island, SC. Set in Melrose among live oaks and Spanish moss, this exceptionally private coastal retreat pairs commanding Atlantic Ocean views with a custom in-ground pool and guest quarters. Offering 4 bedrooms, 4 full baths, 2 half baths and approximately 4,062 square feet, this distinctive property captures the beauty of the South Carolina Lowcountry with abundant wildlife and an extraordinary oceanfront setting.High ceilings, hardwood floors and detailed moldings complement the home's spacious interiors. The enormous primary suite features a fireplace, private balcony and sweeping ocean views-an inviting place to watch the sunrise and unwind to the sound of the waves. Every bedroom has an ensuite bath, providing privacy and comfort for residents and guests alike. Guest quarters offer added flexibility for hosting, while an elevator, tankless water heaters, metal roof and garage parking beneath the home add everyday convenience.Outside, the heated pool creates a private gathering place framed by lush coastal surroundings. From the live oak canopy to the direct ocean views, the setting offers a rare combination of natural beauty, seclusion and upscale island living.Located in an area of Melrose where short-term rentals are allowed, this Daufuskie Island oceanfront home offers options as a primary residence, vacation home or potential vacation rental. Low HOA fees add to its appeal, and Haig Point memberships may be available.Accessible only by boat, Daufuskie Island offers a distinctive escape from the mainland, with an approximately 30-minute ferry ride from Hilton Head or Savannah, depending on service and departure point. Discover the opportunity to own a private oceanfront retreat on one of South Carolina's remaining boat-access-only islands.

106 Martinangel Lane, Daufuskie Island

Courtesy of Premier Properties by Haig Point

$689,000

4 Beds ⋅ 4 Baths ⋅ HILTONHEAD-511542 MLS

Welcome to 13 Masters Drive in the Melrose community on Daufuskie Island. This spacious 4-bedroom, 4-bath home offers the perfect combination of island living, comfort, and investment potential. The open-concept floor plan features generous living spaces, abundant natural light, and four well-appointed bedroom suites, making it ideal for family gatherings or hosting guests.Expansive porches provide the perfect setting to relax and enjoy the peaceful Lowcountry surroundings. The thoughtfully designed layout offers privacy, functionality, and easy indoor-outdoor living.Whether you're searching for a primary residence, second home, or income-producing property, this home presents an excellent opportunity. Its size, layout, and desirable Melrose location make it well-suited for the vacation rental market, offering the potential to generate rental income while enjoying your own island getaway.Experience the unique lifestyle of Daufuskie Island, with beautiful beaches, golf, biking and walking trails, dining, and rich coastal history-all accessible by ferry from Hilton Head Island or Savannah.

13 Masters Drive, Daufuskie Island

Courtesy of Premier Properties by Haig Point

$570,000

4 Beds ⋅ 5 Baths ⋅ HILTONHEAD-511361 MLS

Looking for a Second Home Just 30 Minutes by Boat from Hilton Head with Beach Access and Short-Term Rental Potential? Welcome to 3 Welcome Breeze on Daufuskie Island, a beautifully designed 4-bedroom, 4 full bath, 1 half bath coastal home offering 3,400 square feet of living space on a private 0.6-acre cul-de-sac lot in the Melrose community. Whether you're searching for a vacation home, second home, beach house, or investment property, this home offers the perfect blend of comfort, privacy, and income potential. Short-term rentals are allowed. Designed for gathering family and friends, the spacious two-story floor plan features rich wood floors, multiple primary suites, and a stunning great room with rare pecky cypress walls that showcase classic Lowcountry craftsmanship. A built-in bar, wraparound porch, screened porch, and private patio create inviting spaces for entertaining or simply relaxing after a day at the beach.Located on one of the East Coast's few islands with no bridge, Daufuskie Island offers a peaceful lifestyle where golf carts replace cars and uncrowded beaches, boating, fishing, biking, and world-class golf become part of everyday life. Just 30 minutes by boat from Hilton Head Island and historic Savannah, you'll enjoy easy access while experiencing the privacy and charm of a truly unique coastal community.The flexible layout makes this home ideal for full-time living, a family getaway, or a high-demand vacation rental. With multiple primary suites, there's plenty of room for guests while maintaining privacy and comfort.The Melrose HOA is just $1,100 annually, making ownership even more attractive. If you've been searching for a Daufuskie Island beach house, second home with short-term rental potential, or a peaceful coastal retreat on an island with no bridge, 3 Welcome Breeze is an opportunity you won't want to miss.Schedule your private tour today and discover why so many buyers are choosing Daufuskie Island for its natural beauty, relaxed lifestyle, and one-of-a-kind Lowcountry living.

3 Welcome Breeze Court, Daufuskie Island

Courtesy of Charter One Realty

$850,000

4 Beds ⋅ 4 Baths ⋅ HILTONHEAD-507574 MLS

Experience the best of Lowcountry living in this exceptional 4-bedroom, 3.5-bath residence, perfectly positioned to capture tranquil lagoon and golf course views. Expansive covered front and rear porches provide the ideal setting for relaxing, entertaining, and enjoying the beauty of the surrounding landscape year-round. Inside, soaring ceilings and an open, light-filled floor plan create an inviting atmosphere. The chef's kitchen is thoughtfully designed with abundant workspace, quality finishes, and ample cabinetry, making it perfect for everyday living and entertaining alike. Two spacious primary suites offer exceptional flexibility for multi-generational living, visiting guests, or private owner accommodations. Generous storage throughout the home ensures plenty of room for all your belongings, while the well-designed layout balances comfort and functionality. A rare and valuable feature, the sale includes the adjacent homesite, creating approximately 1.4 acres of privacy and outdoor space. Whether you envision lush gardens, expanded outdoor living areas, or simply enjoying the extra buffer, this unique offering provides endless possibilities. Ideally located just minutes from pristine beaches, shopping, dining, golf, and all the amenities that make the Lowcountry lifestyle so desirable, this is a rare opportunity to own a spacious home with exceptional views, privacy, and room to grow. (Virtual staging has been used in some photographs)

15 Jacks Drive, Daufuskie Island

Courtesy of Charter One Realty

$538,000

3 Beds ⋅ 3 Baths ⋅ HILTONHEAD-510637 MLS

Charming Lowcountry cottage in the heart of Melrose offering 2 bedrooms, 2.5 baths, a spacious sleeping loft with 2 twin beds, and a bright Carolina Room, just a 10 minute walk to Daufuskie's pristine beaches, this beautifully maintained home features pine hardwood flooring, soaring 20 ft ceiling in the great room, fresh interior and exterior paint, and brand new kitchen with new appliances and cabinetry. The open and inviting floor plan is perfect for both everyday living and entertaining. Gather around the cozy wood-burning fireplace indoors or enjoy evenings by the brick firepit outside. A large screened porch overlooks the Melrose golf course creating a peaceful setting to relax and unwind. Conveniently located just a short golf cart ride from Freeport Marina, this property provides easy access to the best of island living. Enjoy fishing, birdwatching, biking, boating, historic landmarks, and miles of uncrowded beaches. Whether you're seeking a primary residence, vacation retreat, or incom producing rental investment, this exceptional property offers the perfect combination of comfort, character, and the laid-back lifestyle that makes Daufuskie Island so special.

8 Volunteers Ridge, Daufuskie Island

Courtesy of Charter One Realty

$629,500

4 Beds ⋅ 3.5 Baths ⋅ 26015033 MLS

**Seller is offering $2,500 in concessions toward buyer's closing costs, rate buy-down, or upgrades.**There's a certain charm you simply can't recreate in new construction, and 946 Melrose has it in spades. From the beautiful Charleston brick flooring and timeless architectural details to the solid construction and thoughtful layout, this home offers the character and craftsmanship that make a house feel like home.The main home features three bedrooms upstairs, plus a massive FROG (finished room over the garage) that offers endless flexibility. Use it as a fourth bedroom, home office, gym, media room, playroom, or whatever best fits your lifestyle.The heart of the home is a thoughtfully designed kitchen featuring high-quality cabinetry, ample storage, and timeless finishes. Throughout the main living spaces, you'll find architectural details that add both character and warmth, including custom built-ins, a coffered ceiling, and a classic fireplace that creates a natural gathering space. These are the kinds of details that give the home a sense of craftsmanship and permanence that's difficult to replicate in newer construction. One of the home's standout features is the attached garage that has been converted into a separate living space with its own bathroom. With its private setup, it's ideal for an in-law suite, guest quarters, or multigenerational living. It could also provide an opportunity to be an income-producing rental. Outside, you'll find a covered carport and a large detached outbuilding with electricity, offering additional options for storage, hobbies, a workshop, or workspace. The spacious living areas open naturally to an inviting screened porch, creating an ideal setting for morning coffee, casual dinners, or relaxing with friends. Combined with the established setting, mature landscaping, and flexible floor plan, 946 Melrose offers something that's increasingly hard to find: a well-built home with character, quality, and room to make it your own.

946 Melrose Drive, Charleston

Listing courtesy of Listing Agent: Tangi Thomas from Listing Office: Jacobsen Realty.

$849,000

5 Beds ⋅ 4 Baths ⋅ HILTONHEAD-506776 MLS

Embrace the quiet luxury of island living at its finest on Daufuskie Island. Nestled along the scenic fairways of the Melrose golf course, this beautifully maintained & fully furnished 5-bedroom, 3.5-bath home offers 3,356 square feet of thoughtfully designed, stately living space - where privacy, nature, & effortless comfort converge. Accessible only by boat, Daufuskie offers a rare escape from the bustle of nearby Hilton Head Island and Savannah - a place where quiet beaches, maritime forests, & a slower pace of life define each day. A gracious front veranda welcomes you into an open-concept floor plan designed for both relaxed living & effortless entertaining. The spacious first-floor primary suite offers direct access to the screened porch, creating a seamless indoor-outdoor retreat. A 2nd bedroom/office on the first floor as well At the heart of the home, a chef's kitchen with an oversized island, convection ovens, wine cooler, and expansive pantry flows beautifully into the living and dining areas. The screened back porch provides the perfect setting for morning coffee or evening gatherings under the coastal sky. Enjoy the serene sound of the nearby ocean waves from both the front & back porches. Upstairs, three generously sized bedrooms - each with custom walk-in closets - are complemented by two full baths & a charming sitting area overlooking the surrounding maritime forest, offering a peaceful vantage point from every angle. The ground level features conditioned flex space ideal for storage, a workshop, or creative pursuits, along with convenient two garages. Located just a short bike or golf cart ride from Melrose's pristine beaches, community pools, dining, & fitness amenities, this home delivers the best of coastal living. Additional highlights include: Fully furnished and move-in ready; High-speed fiber optic internet for remote work and streaming; Water/sewer, electric utilities. FEMA Flood Insurance is not available. Strong potential as a primary residence, vacation home, or income-producing property. Optional membership opportunities may be available at Haig Point Club, featuring world-class golf courses designed by Rees Jones, tennis, pickleball, equestrian facilities, fitness center, beach club, dining, and 24/7 ferry service. This is more than a home - it's a lifestyle! Discover your private island retreat and experience the unmatched beauty, tranquility, and community spirit that make Daufuskie truly special.

30 Captain Monroe Lane, Daufuskie Island

Courtesy of Daufuskie Properties Realty LLC

$1,290,000

5 Beds ⋅ 5 Baths ⋅ HILTONHEAD-502252 MLS

A rare oceanfront retreat with over $100k in short-term rentals awaits on this peaceful bridge-less island, where coastal charm and comfort meet the simple beauty of a bohemian island life. This fully renovated one-story, 5-bedroom, 5-bath home offers open, light-filled spaces designed for easy living and a connection to the outdoors. Every detail has been thoughtfully updated, featuring wide-plank flooring, shiplap walls, and soft coastal tones that reflect the surrounding sea and sky. Fully remodeled in 2021, this home has a new roof, 2 tankless water heaters, and sits just mere feet from the uncrowded beaches of Daufuskie. Furnished in a relaxed coastal farmhouse style, the home is being sold completely turn-key with inviting furniture and décor that complements the natural setting. The open-concept layout includes a spacious living and dining area that flow into a bright, modern kitchen with quartz counters, stainless appliances, and an abundance of cabinets. Multiple primary suites are perfect for large families and groups with the large screened porch serving as the centerpiece of the home--perfect for enjoying ocean breezes, morning coffee, or quiet evenings listening to the waves. It's a gathering space made for both relaxation and time together. Two new, electric golf carts are available to purchase, making travel around the island simple and enjoyable-whether heading to the ferry, the beach, or a nearby café. With a strong short-term rental history, the property is ready for continued income or as a personal getaway. This home captures the best of island living--fresh air, open space, and the peaceful rhythm of the tides. Accessible only by boat, Daufuskie Island offers a rare opportunity to slow down, reconnect, and enjoy coastal living the way it was meant to be--comfortable, natural, and full of everyday beauty.Full Club memberships may be available to purchase from neighboring Haig Point--amenities there include Rees Jones Golf Courses, tennis/pickleball, equestrian center, fitness center, beach club, 24/7 ferry access, two restaurants, and much more!

100 Ave Of Oaks, Daufuskie Island

Courtesy of Charter One Realty

$785,000

8 Beds ⋅ 7 Baths ⋅ HILTONHEAD-455087 MLS

Looking for that special home to make a family retreat or investment income property? Look no further! Wonderful eight bedroom home with huge kitchen, two great rooms and screened porches make this a great place for family reunions or multifamily vacations. High speed fiber optics make working from home a breeze and streaming movies and TV a cinch. Easily accommodate food for even the busiest of gatherings in the huge kitchen. It's just a short cart ride to the unspoiled beaches that make Daufuskie a dream vacation. There is an optional, seasonal pool and fitness membership with discounted rates for Melrose property owners.

12 Freeport Court, Daufuskie Island

Courtesy of Daufuskie Properties Realty LLC

$799,000

5 Beds ⋅ 6 Baths ⋅ HILTONHEAD-445973 MLS

Discover a beautiful island getaway that can only be reached by boat, offering three miles of untouched, pristine beaches along the stunning Atlantic Ocean. This peaceful escape is perfect for those seeking tranquility and natural beauty.The home is ideally situated just a quick five-minute golf cart ride from the beach. You'll find yourself close to beloved local spots, including restaurants, artists, a distillery, an ice cream stand, and more. Embrace the laid-back island lifestyle, where bikes and golf carts are the primary modes of transportation. Life here moves at a slower, safer, and much less stressful pace-affectionately known as "Daufuskie Time."Take in the island's unspoiled natural beauty. Watch playful dolphins frolic in the surf as Bald Eagles soar overhead. Spend your days searching for centuries-old sharks' teeth or watching children build sandcastles on the beach. For the adventurous, try your hand at casting a net and shrimping for your dinner right off the shoreline.This exceptional home features a large, open floor plan with elegant French doors that lead to an expansive porch, complete with an outdoor kitchen-making it perfect for entertaining family and friends. With five bedrooms and 5.5 baths, there's plenty of space for everyone. The primary bedroom includes a luxurious separate tub and shower. Scrapped hard-wood floors add charm and warmth to this versatile home.Fully furnished and move in ready it's an excellent opportunity whether you're seeking a family retreat, a primary residence, or a property with strong rental income potential. Additional conveniences include parking under the house, high speed fiber optic to keep you in touch with the outside world and perfect for streaming. In-ground water/sewer and electric and an inground propane tank make living on the island easy.The island boasts a rich historical and cultural heritage, including stories from the plantation era, the struggles and traditions of enslaved Americans known as Gullah, and the region's cotton and oyster industries. The island also played a strategic role in both the American Revolution and the Civil War, adding depth and intrigue to its unique character. All of this and more can be found at the island's Historical Museum.The island is as unique as you are. Come visit and see for yourself why so many people fall in love with Daufuskie.

33 Masters Drive, Daufuskie Island

Courtesy of Daufuskie Properties Realty LLC

Start Your Search

We do not attempt to independently verify the currency, completeness, accuracy or authenticity of the data contained herein. It may be subject to transcription and transmission errors. Accordingly, the data is provided on an “as is” “as available” basis only and may not reflect all real estate activity in the market. © 2026 REsides, Inc. All rights reserved. Certain information contained herein is derived from information, which is the licensed property of, and copyrighted by, REsides, Inc.

This information is deemed reliable, but not guaranteed. Neither the Lowcountry Regional MLS, nor the listing broker, nor their agents or subagents are responsible for the accuracy of the information. The buyer is responsible for verifying all information. This information is provided by the Lowcountry Regional MLS for use by its members and is not intended for use for any other purpose.